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Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome
Caspase-11 is a cytosolic sensor and protease that drives innate immune responses to the bacterial cell wall component, LPS. Caspase-11 provides defence against cytosolic Gram-negative bacteria; however, excessive caspase-11 responses contribute to murine endotoxic shock. Upon sensing LPS, caspase-1...
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| Publicado no: | Life Sci Alliance |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Life Science Alliance LLC
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6284101/ https://ncbi.nlm.nih.gov/pubmed/30564782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800237 |
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