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Cholesterol enhances influenza binding avidity by controlling nanoscale receptor clustering
Influenza virus infects cells by binding to sialylated glycans on the cell surface. While the chemical structure of these glycans determines hemagglutinin–glycan binding affinity, bimolecular affinities are weak, so binding is avidity-dominated and driven by multivalent interactions. Here, we show t...
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| Udgivet i: | Chem Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Royal Society of Chemistry
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5839467/ https://ncbi.nlm.nih.gov/pubmed/29520318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03236f |
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