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Bacterial Branched-Chain Amino Acid Biosynthesis: Structures, Mechanisms, and Drugability

The eight enzymes responsible for the biosynthesis of the three branched-chain amino acids (l-isoleucine, l-leucine, and l-valine) were identified decades ago using classical genetic approaches based on amino acid auxotrophy. This review will highlight the recent progress in the determination of the...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Amorim Franco, Tathyana M., Blanchard, John S.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839172/
https://ncbi.nlm.nih.gov/pubmed/28977745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00849
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