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Branched-Chain Amino Acid Substitutions in the Biosynthesis of the Antibiotic Actinomycin

Actinomycins normally contain N-methyl-l-valine and either d-valine, d-alloisoleucine or both amino acids in the molecule. During antibiotic formation in a medium supplemented with one of the four isoleucine stereoisomers, Streptomyces parvulus and S. chrysomallus form complex actinomycin mixtures (...

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Detalles Bibliográficos
Main Authors: Yajima, Takehiko, Mason, Kaarin T., Katz, Edward
Formato: Artigo
Idioma:Inglês
Publicado: 1975
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC429225/
https://ncbi.nlm.nih.gov/pubmed/50761
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