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The competitive nature of signal transducer and activator of transcription complex formation drives phenotype switching of T cells

Signal transducers and activators of transcription (STATs) are key molecular determinants of T‐cell fate and effector function. Several inflammatory diseases are characterized by an altered balance of T‐cell phenotypes and cytokine secretion. STATs, therefore, represent viable therapeutic targets in...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Sadreev, Ildar I., Chen, Michael Z. Q., Umezawa, Yoshinori, Biktashev, Vadim N., Kemper, Claudia, Salakhieva, Diana V., Welsh, Gavin I., Kotov, Nikolay V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838427/
https://ncbi.nlm.nih.gov/pubmed/29030870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12851
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