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The competitive nature of signal transducer and activator of transcription complex formation drives phenotype switching of T cells

Signal transducers and activators of transcription (STATs) are key molecular determinants of T‐cell fate and effector function. Several inflammatory diseases are characterized by an altered balance of T‐cell phenotypes and cytokine secretion. STATs, therefore, represent viable therapeutic targets in...

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Dades bibliogràfiques
Publicat a:Immunology
Autors principals: Sadreev, Ildar I., Chen, Michael Z. Q., Umezawa, Yoshinori, Biktashev, Vadim N., Kemper, Claudia, Salakhieva, Diana V., Welsh, Gavin I., Kotov, Nikolay V.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838427/
https://ncbi.nlm.nih.gov/pubmed/29030870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12851
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