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Modulation of Oral Bioavailability and Metabolism for Closely Related Cyclic Hexapeptides

ABSTRACT: Recently, a variety of studies concerned with the permeability and oral bioavailability of cyclic peptides have been reported. In particular, strategies aiming at modifying peptides to maintain or to enhance solubility while enabling permeability constitute a significant challenge, but are...

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Detalhes bibliográficos
Publicado no:Int J Pept Res Ther
Main Authors: Vorherr, Thomas, Lewis, Ian, Berghausen, Joerg, Desrayaud, Sandrine, Schaefer, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838147/
https://ncbi.nlm.nih.gov/pubmed/29527142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10989-017-9590-8
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