Vitamin D treatment attenuates cardiac FGF23/FGFR4 signaling and hypertrophy in uremic rats

Background. Vitamin D deficiency and excess of circulating fibroblast growth factor 23 (FGF23) contribute to cardiovascular mortality in patients with chronic kidney disease (CKD). FGF23 activates FGF receptor 4 and (FGFR4) calcineurin/nuclear factor of activated T cells (NFAT) signaling in cardiac...

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Detalhes bibliográficos
Publicado no:Nephrol Dial Transplant
Main Authors: Leifheit-Nestler, Maren, Grabner, Alexander, Hermann, Laura, Richter, Beatrice, Schmitz, Karin, Fischer, Dagmar-Christiane, Yanucil, Christopher, Faul, Christian, Haffner, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837317/
https://ncbi.nlm.nih.gov/pubmed/28339837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfw454
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