Propionibacterium acnes induces intervertebral disc degeneration by promoting nucleus pulposus cell apoptosis via the TLR2/JNK/mitochondrial-mediated pathway

Evidence suggests that intervertebral disc degeneration (IVDD) can be induced by Propionibacterium acnes (P. acnes), although the underlying mechanisms are unclear. In this study, we analyzed the pathological changes in degenerated human intervertebral discs (IVDs) infected with P. acnes. Compared w...

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Detalhes bibliográficos
Publicado no:Emerg Microbes Infect
Main Authors: Lin, Yazhou, Jiao, Yucheng, Yuan, Ye, Zhou, Zezhu, Zheng, Yuehuan, Xiao, Jiaqi, Li, Changwei, Chen, Zhe, Cao, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837142/
https://ncbi.nlm.nih.gov/pubmed/29323102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-017-0002-0
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