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Propionibacterium acnes induces intervertebral discs degeneration by increasing MMP-1 and inhibiting TIMP-1 expression via the NF-κB pathway
Emerging evidence suggests that Propionibacterium acnes (P. acnes) may be a new pathogen implicated in intervertebral disc degeneration (IVDD), although the underlying mechanisms are unclear. Since the most significant biochemical change of IVDD is inability of the extracellular matrix (ECM) synthes...
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| Publicado no: | Int J Clin Exp Pathol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
e-Century Publishing Corporation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6962859/ https://ncbi.nlm.nih.gov/pubmed/31949722 |
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