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Propionibacterium acnes induces intervertebral discs degeneration by increasing MMP-1 and inhibiting TIMP-1 expression via the NF-κB pathway

Emerging evidence suggests that Propionibacterium acnes (P. acnes) may be a new pathogen implicated in intervertebral disc degeneration (IVDD), although the underlying mechanisms are unclear. Since the most significant biochemical change of IVDD is inability of the extracellular matrix (ECM) synthes...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Clin Exp Pathol
Prif Awduron: Zheng, Yuehuan, Lin, Yazhou, Chen, Zhe, Jiao, Yucheng, Yuan, Ye, Li, Changwei, Xu, Xiangyang, Cao, Peng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: e-Century Publishing Corporation 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962859/
https://ncbi.nlm.nih.gov/pubmed/31949722
Tagiau: Ychwanegu Tag
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