Propionibacterium acnes induces intervertebral disc degeneration by promoting nucleus pulposus cell apoptosis via the TLR2/JNK/mitochondrial-mediated pathway

Evidence suggests that intervertebral disc degeneration (IVDD) can be induced by Propionibacterium acnes (P. acnes), although the underlying mechanisms are unclear. In this study, we analyzed the pathological changes in degenerated human intervertebral discs (IVDs) infected with P. acnes. Compared w...

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Vydáno v:Emerg Microbes Infect
Hlavní autoři: Lin, Yazhou, Jiao, Yucheng, Yuan, Ye, Zhou, Zezhu, Zheng, Yuehuan, Xiao, Jiaqi, Li, Changwei, Chen, Zhe, Cao, Peng
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837142/
https://ncbi.nlm.nih.gov/pubmed/29323102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-017-0002-0
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