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Sterol oxidation mediates stress-responsive Vms1 translocation to mitochondria
Vms1 translocates to damaged mitochondria in response to stress, whereupon its binding partner, Cdc48, contributes to mitochondrial protein homeostasis. Mitochondrial targeting of Vms1 is mediated by its conserved Mitochondrial Targeting Domain (MTD), which in unstressed conditions is inhibited by i...
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| Veröffentlicht in: | Mol Cell |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5837041/ https://ncbi.nlm.nih.gov/pubmed/29149595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.10.022 |
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