Sterol oxidation mediates stress-responsive Vms1 translocation to mitochondria

Vms1 translocates to damaged mitochondria in response to stress, whereupon its binding partner, Cdc48, contributes to mitochondrial protein homeostasis. Mitochondrial targeting of Vms1 is mediated by its conserved Mitochondrial Targeting Domain (MTD), which in unstressed conditions is inhibited by i...

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Bibliografiska uppgifter
I publikationen:Mol Cell
Huvudupphovsmän: Nielson, Jason. R., Fredrickson, Eric K., Waller, T. Cameron, Rendón, Olga Zurita, Schubert, Heidi L., Lin, Zhenjian, Hill, Christopher P., Rutter, Jared
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837041/
https://ncbi.nlm.nih.gov/pubmed/29149595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.10.022
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