Vms1p is a release factor for the ribosome-associated quality control complex

Eukaryotic cells employ the ribosome-associated quality control complex (RQC) to maintain homeostasis despite defects that cause ribosomes to stall. The RQC comprises the E3 ubiquitin ligase Ltn1p, the ATPase Cdc48p, Rqc1p, and Rqc2p. Upon ribosome stalling and splitting, the RQC assembles on the 60...

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Pubblicato in:Nat Commun
Autori principali: Zurita Rendón, Olga, Fredrickson, Eric K., Howard, Conor J., Van Vranken, Jonathan, Fogarty, Sarah, Tolley, Neal D., Kalia, Raghav, Osuna, Beatriz A., Shen, Peter S., Hill, Christopher P., Frost, Adam, Rutter, Jared
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989216/
https://ncbi.nlm.nih.gov/pubmed/29875445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04564-3
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