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Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress
Oncogene-induced DNA replication stress contributes critically to the genomic instability present in cancer1–4. However, elucidating how oncogenes deregulate DNA replication has been impeded by the difficulty in mapping replication initiation sites on the human genome. In this study, using a sensiti...
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| izdano v: | Nature |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5837010/ https://ncbi.nlm.nih.gov/pubmed/29466339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25507 |
| Oznake: |
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