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Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stress

Human cancers are characterized by the presence of genomic instability. Recently, two studies have catalogued the presence of a specific class of genomic aberrations, large deletions and insertions, in a few thousand human cancers and reported that most of the prevalent recurrent focal deletions tar...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Dereli‐Öz, Aygül, Versini, Gwennaelle, Halazonetis, Thanos D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528318/
https://ncbi.nlm.nih.gov/pubmed/21641882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.05.002
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