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Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stress

Human cancers are characterized by the presence of genomic instability. Recently, two studies have catalogued the presence of a specific class of genomic aberrations, large deletions and insertions, in a few thousand human cancers and reported that most of the prevalent recurrent focal deletions tar...

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Bibliografski detalji
Izdano u:Mol Oncol
Glavni autori: Dereli‐Öz, Aygül, Versini, Gwennaelle, Halazonetis, Thanos D.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528318/
https://ncbi.nlm.nih.gov/pubmed/21641882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.05.002
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