טוען...
A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells
Embryonic stem cells (ESCs) represent a transient biological state, where pluripotency is coupled with fast proliferation. ESCs display a constitutively active DNA damage response (DDR), but its molecular determinants have remained elusive. Here we show in cultured ESCs and mouse embryos that H2AX p...
שמור ב:
| הוצא לאור ב: | Nat Commun |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4756311/ https://ncbi.nlm.nih.gov/pubmed/26876348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10660 |
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