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Reductive Decarboxylative Alkynylation of N-Hydroxyphthalimide Esters with Bromoalkynes

A new method for the synthesis of terminal and internal alkynes from the nickel-catalyzed decarboxylative coupling of N-hydroxyphthalimide esters (NHP esters) and bromoalkynes is presented. This reductive cross-electrophile coupling is the first to use a C(sp)-X electrophile, and appears to proceed...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Huang, Liangbin, Olivares, Astrid M., Weix, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836783/
https://ncbi.nlm.nih.gov/pubmed/28782860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201706781
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