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Pharmacological inhibition of EZH2 disrupts the female germline epigenome

BACKGROUND: Recently discovered drugs that target epigenetic modifying complexes are providing new treatment options for a range of cancers that affect patients of reproductive age. Although these drugs provide new therapies, it is likely that they will also affect epigenetic programming in sperm an...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Prokopuk, Lexie, Hogg, Kirsten, Western, Patrick S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836460/
https://ncbi.nlm.nih.gov/pubmed/29515677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0465-4
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