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PRC2 is required for extensive reorganization of H3K27me3 during epigenetic reprogramming in mouse fetal germ cells

BACKGROUND: Defining how epigenetic information is established in the germline during fetal development is key to understanding how epigenetic information is inherited and impacts on evolution and human health and disease. RESULTS: Here, we show that Polycomb Repressive Complex 2 is transiently loca...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Prokopuk, Lexie, Stringer, Jessica M., Hogg, Kirsten, Elgass, Kirstin D., Western, Patrick S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319108/
https://ncbi.nlm.nih.gov/pubmed/28239420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-017-0113-9
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