Anti-apoptotic effects of IGF-I on mortality and dysmorphogenesis in tbx5-deficient zebrafish embryos

BACKGROUND: Tbx5 deficiency in zebrafish causes several abnormal phenotypes of the heart and pectoral fins. It has been reported that exogenous human growth hormone can enhance expression of downstream mediators in the growth hormone and insulin-like growth factor I (IGF-I) pathway and partially res...

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Publicat a:BMC Dev Biol
Autors principals: Tsai, Tzu-Chun, Shih, Chun-Che, Chien, Hsin-Ping, Yang, An-Hang, Lu, Jenn-Kan, Lu, Jen-Her
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836385/
https://ncbi.nlm.nih.gov/pubmed/29506474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12861-017-0161-1
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