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Anti-apoptotic effects of IGF-I on mortality and dysmorphogenesis in tbx5-deficient zebrafish embryos

BACKGROUND: Tbx5 deficiency in zebrafish causes several abnormal phenotypes of the heart and pectoral fins. It has been reported that exogenous human growth hormone can enhance expression of downstream mediators in the growth hormone and insulin-like growth factor I (IGF-I) pathway and partially res...

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Bibliografiske detaljer
Udgivet i:BMC Dev Biol
Main Authors: Tsai, Tzu-Chun, Shih, Chun-Che, Chien, Hsin-Ping, Yang, An-Hang, Lu, Jenn-Kan, Lu, Jen-Her
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836385/
https://ncbi.nlm.nih.gov/pubmed/29506474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12861-017-0161-1
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