Anti-apoptotic effects of IGF-I on mortality and dysmorphogenesis in tbx5-deficient zebrafish embryos

BACKGROUND: Tbx5 deficiency in zebrafish causes several abnormal phenotypes of the heart and pectoral fins. It has been reported that exogenous human growth hormone can enhance expression of downstream mediators in the growth hormone and insulin-like growth factor I (IGF-I) pathway and partially res...

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Detalhes bibliográficos
Publicado no:BMC Dev Biol
Main Authors: Tsai, Tzu-Chun, Shih, Chun-Che, Chien, Hsin-Ping, Yang, An-Hang, Lu, Jenn-Kan, Lu, Jen-Her
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836385/
https://ncbi.nlm.nih.gov/pubmed/29506474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12861-017-0161-1
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