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Repair of a site-specific DNA cleavage: old-school lessons for Cas9-mediated gene editing
CRISPR/Cas9-mediated gene editing may involve nonhomologous end-joining to create various insertion/deletions (indels) or may employ homologous recombination to modify precisely the target DNA sequence. Our understanding of these processes has been guided by earlier studies using other site-specific...
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| Vydáno v: | ACS Chem Biol |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5835394/ https://ncbi.nlm.nih.gov/pubmed/29083855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00760 |
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