UVA Irradiation Enhances Brusatol-Mediated Inhibition of Melanoma Growth by Downregulation of the Nrf2-Mediated Antioxidant Response

Brusatol (BR) is a potent inhibitor of Nrf2, a transcription factor that is highly expressed in cancer tissues and confers chemoresistance. UVA-generated reactive oxygen species (ROS) can damage both normal and cancer cells and may be of potential use in phototherapy. In order to provide an alternat...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Wang, Mei, Shi, Guangwei, Bian, Chunxiang, Nisar, Muhammad Farrukh, Guo, Yingying, Wu, Yan, Li, Wei, Huang, Xiao, Jiang, Xuemei, Bartsch, Jörg W., Ji, Ping, Zhong, Julia Li
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835260/
https://ncbi.nlm.nih.gov/pubmed/29670684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9742154
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