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The p75(NTR) and its carboxyl‐terminal fragment exert opposing effects on melanoma cell proliferation and apoptosis via modulation of the NF‐κB pathway

The p75 neurotrophin receptor (p75(NTR)), a member of the tumor necrosis factor superfamily of receptors, is sensitive to proteolysis and has been observed to be expressed in various cancers. However, the roles of p75(NTR) and its proteolytic fragments in tumorigenesis remain incompletely understood...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Zhong, Maojiao, Wang, Yingying, Muhammad, Farrukh Nisar, Gao, Jing, Bian, Chunxiang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780107/
https://ncbi.nlm.nih.gov/pubmed/33247998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13047
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