The Antiaging Activity of Ergothioneine in UVA-Irradiated Human Dermal Fibroblasts via the Inhibition of the AP-1 Pathway and the Activation of Nrf2-Mediated Antioxidant Genes

UVA irradiation induced ROS-mediated photo damage to the human skin leading to coarseness, wrinkling, pigmentation, and cutaneous malignancies. We investigated the dermatoprotective efficacies of submicromolar concentrations of ergothioneine (EGT, 0.125-0.5 μM), which occurs naturally as a sulfur-co...

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Dettagli Bibliografici
Pubblicato in:Oxid Med Cell Longev
Autori principali: Hseu, You-Cheng, Vudhya Gowrisankar, Yugandhar, Chen, Xuan-Zao, Yang, Yi-Chen, Yang, Hsin-Ling
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038158/
https://ncbi.nlm.nih.gov/pubmed/32104530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2576823
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