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Yoda1-induced phosphorylation of Akt and ERK1/2 does not require Piezo1 activation

Piezo1 is a mechanosensitive cation channel that is activated by shear stress in endothelial cells (ECs). It has been shown to mediate shear-induced EC responses, including increased calcium influx, and vascular functions, such as vascular tone and blood pressure. Yoda1, a selective Piezo1 activator...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: dela Paz, Nathaniel G., Frangos, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835220/
https://ncbi.nlm.nih.gov/pubmed/29428723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.02.058
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