Irradiation Enhances Abscopal Anti-tumor Effects of Antigen-Specific Immunotherapy through Regulating Tumor Microenvironment

Ionizing radiation therapy is a well-established method of eradicating locally advanced tumors. Here, we examined whether local RT enhanced the potency of an antigen-specific DNA vaccine, and we investigated the possible underlying mechanism. Using the HPV16 E6/E7(+) syngeneic TC-1 tumor, we evaluat...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther
Asıl Yazarlar: Chang, Ming-Cheng, Chen, Yu-Li, Lin, Han-Wei, Chiang, Ying-Cheng, Chang, Chi-Fang, Hsieh, Shu-Feng, Chen, Chi-An, Sun, Wei-Zen, Cheng, Wen-Fang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2018
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835145/
https://ncbi.nlm.nih.gov/pubmed/29248428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.11.011
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