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Fusion Protein Vaccines Targeting Two Tumor Antigens Generate Synergistic Anti-Tumor Effects

INTRODUCTION: Human papillomavirus (HPV) has been consistently implicated in causing several kinds of malignancies, and two HPV oncogenes, E6 and E7, represent two potential target antigens for cancer vaccines. We developed two fusion protein vaccines, PE(ΔIII)/E6 and PE(ΔIII)/E7 by targeting these...

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Detalhes bibliográficos
Main Authors: Cheng, Wen-Fang, Chang, Ming-Cheng, Sun, Wei-Zen, Jen, Yu-Wei, Liao, Chao-Wei, Chen, Yun-Yuan, Chen, Chi-An
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772923/
https://ncbi.nlm.nih.gov/pubmed/24058440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071216
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