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Depletion of Regulatory T Lymphocytes Reverses the Imbalance between Pro- and Anti-Tumor Immunities via Enhancing Antigen-Specific T Cell Immune Responses

BACKGROUND: The regulatory T cells (Tregs) can actively suppress the immune responses. However, literature about detailed changes of host effective and suppressive immunities before and after depletion of Tregs in ovarian carcinomas, is rare. MATERIALS AND METHODS: Ovarian cancer patients and the as...

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Autors principals: Chen, Yu-Li, Chang, Ming-Cheng, Chen, Chi-An, Lin, Han-Wei, Cheng, Wen-Fang, Chien, Chung-Liang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474819/
https://ncbi.nlm.nih.gov/pubmed/23082146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047190
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