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Rh-Catalyzed Conjugate Addition of Aryl and Alkenyl Boronic Acids to α-Methylene-β-lactones: Stereoselective Synthesis of trans-3,4-Disubstituted β-Lactones

A one-step preparation of 3,4-disubstituted β-lactones through Rh-catalyzed conjugate addition of aryl or alkenyl boronic acids to α-methylene-β-lactones is described. The operationally simple, stereoselective transformation provides a broad range of β-lactones from individual α-methylene-β-lactone...

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Bibliografske podrobnosti
izdano v:Org Lett
Main Authors: Malapit, Christian A., Luvaga, Irungu K., Caldwell, Donald R., Schipper, Nicholas K., Howell, Amy R.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834916/
https://ncbi.nlm.nih.gov/pubmed/28809569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01994
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