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Lupus-like autoimmune disease caused by a lack of Xkr8, a caspase-dependent phospholipid scramblase
Apoptotic cells expose phosphatidylserine (PtdSer) on their cell surface and are recognized by macrophages for clearance. Xkr8 is a scramblase that exposes PtdSer in a caspase-dependent manner. Here, we found that among the three Xkr members with caspase-dependent scramblase activity, mouse hematopo...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5834722/ https://ncbi.nlm.nih.gov/pubmed/29440417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720732115 |
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