Targeting the cMET pathway augments radiation response without adverse effect on hearing in NF2 schwannoma models

Neurofibromatosis type II (NF2) is a disease that needs new solutions. Vestibular schwannoma (VS) growth causes progressive hearing loss, and the standard treatment, including surgery and radiotherapy, can further damage the nerve. There is an urgent need to identify an adjunct therapy that, by enha...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Zhao, Yingchao, Liu, Pinan, Zhang, Na, Chen, Jie, Landegger, Lukas D., Wu, Limeng, Zhao, Fu, Zhao, Yanxia, Zhang, Yanling, Zhang, Jing, Fujita, Takeshi, Stemmer-Rachamimov, Anat, Ferraro, Gino B., Liu, Hao, Muzikansky, Alona, Plotkin, Scott R., Stankovic, Konstantina M., Jain, Rakesh K., Xu, Lei
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
PNAS Plus
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834719/
https://ncbi.nlm.nih.gov/pubmed/29440379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719966115
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