Targeting the cMET pathway augments radiation response without adverse effect on hearing in NF2 schwannoma models

Neurofibromatosis type II (NF2) is a disease that needs new solutions. Vestibular schwannoma (VS) growth causes progressive hearing loss, and the standard treatment, including surgery and radiotherapy, can further damage the nerve. There is an urgent need to identify an adjunct therapy that, by enha...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhao, Yingchao, Liu, Pinan, Zhang, Na, Chen, Jie, Landegger, Lukas D., Wu, Limeng, Zhao, Fu, Zhao, Yanxia, Zhang, Yanling, Zhang, Jing, Fujita, Takeshi, Stemmer-Rachamimov, Anat, Ferraro, Gino B., Liu, Hao, Muzikansky, Alona, Plotkin, Scott R., Stankovic, Konstantina M., Jain, Rakesh K., Xu, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834719/
https://ncbi.nlm.nih.gov/pubmed/29440379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719966115
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