Sophora flavescens protects against mycobacterial Trehalose Dimycolate-induced lung granuloma by inhibiting inflammation and infiltration of macrophages

The immune system responds to Mycobacterium tuberculosis (MTB) infection by forming granulomas to quarantine the bacteria from spreading. Granuloma-mediated inflammation is a cause of lung destruction and disease transmission. Sophora flavescens (SF) has been demonstrated to exhibit bactericidal act...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Dehua, Chan, Ben Chung-Lap, Cheng, Ling, Tsang, Miranda Sin-Man, Zhu, Jing, Wong, Chun-Wai, Jiao, Delong, Chan, Helen Yau-Tsz, Leung, Ping Chung, Lam, Christopher Wai-Kei, Wong, Chun Kwok
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834626/
https://ncbi.nlm.nih.gov/pubmed/29500453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22286-w
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