In Vivo Administration of Mycobacterial Cord Factor (Trehalose 6,6′-Dimycolate) Can Induce Lung and Liver Granulomas and Thymic Atrophy in Rabbits

Trehalose 6,6′-dimycolate (TDM) is a cell surface molecule of Mycobacterium tuberculosis. TDM induced a loss of body weight and prominent granulomas in the liver and lungs by the intravenous injection of TDM into rabbits. TDM also induced atrophy of the thymus and spleen due to apoptosis. By contras...

詳細記述

書誌詳細

出版年:	Infect Immun
主要な著者:	Hamasaki, Naoko, Isowa, Ko-Ichi, Kamada, Kohachi, Terano, Yoshitake, Matsumoto, Takayuki, Arakawa, Tetsuo, Kobayashi, Kazuo, Yano, Ikuya
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2000
主題:	Molecular and Cellular Pathogenesis
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97662/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10816531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.6.3704-3709.2000
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