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Phenytoin inhibits necroptosis
Receptor-interacting protein kinases 1 and 3 (RIPK1/3) have best been described for their role in mediating a regulated form of necrosis, referred to as necroptosis. During this process, RIPK3 phosphorylates mixed lineage kinase domain-like (MLKL) to cause plasma membrane rupture. RIPK3-deficient mi...
Gorde:
| Argitaratua izan da: | Cell Death Dis |
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| Egile Nagusiak: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group UK
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5834524/ https://ncbi.nlm.nih.gov/pubmed/29500402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0394-3 |
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