Phenytoin inhibits necroptosis

Receptor-interacting protein kinases 1 and 3 (RIPK1/3) have best been described for their role in mediating a regulated form of necrosis, referred to as necroptosis. During this process, RIPK3 phosphorylates mixed lineage kinase domain-like (MLKL) to cause plasma membrane rupture. RIPK3-deficient mi...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: von Mässenhausen, Anne, Tonnus, Wulf, Himmerkus, Nina, Parmentier, Simon, Saleh, Danish, Rodriguez, Diego, Ousingsawat, Jiraporn, Ang, Rosalind L., Weinberg, Joel M., Sanz, Ana B., Ortiz, Alberto, Zierleyn, Adrian, Becker, Jan Ulrich, Baratte, Blandine, Desban, Nathalie, Bach, Stéphane, Schiessl, Ina Maria, Nogusa, Shoko, Balachandran, Siddharth, Anders, Hans Joachim, Ting, Adrian T., Bleich, Markus, Degterev, Alexei, Kunzelmann, Karl, Bornstein, Stefan R., Green, Douglas R., Hugo, Christian, Linkermann, Andreas
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834524/
https://ncbi.nlm.nih.gov/pubmed/29500402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0394-3
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