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Necroptosis controls NET generation and mediates complement activation, endothelial damage, and autoimmune vasculitis
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) constitutes life-threatening autoimmune diseases affecting every organ, including the kidneys, where they cause necrotizing crescentic glomerulonephritis. ANCA activates neutrophils and activated neutrophils damage the endotheliu...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692554/ https://ncbi.nlm.nih.gov/pubmed/29078325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708247114 |
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