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Bayesian Networks: A New Approach to Predict Therapeutic Range Achievement of Initial Cyclosporine Blood Concentration After Pediatric Hematopoietic Stem Cell Transplantation

BACKGROUND: Pediatric hematopoietic stem cell transplantation (HSCT) allows the treatment of numerous diseases, both malignant and non-malignant. Cyclosporine, a narrow therapeutic index drug, is the major immunosuppressant used to prevent graft-versus-host disease (GVHD), but may also cause severe...

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Vydáno v:Drugs R D
Hlavní autoři: Leclerc, Vincent, Ducher, Michel, Bleyzac, Nathalie
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833907/
https://ncbi.nlm.nih.gov/pubmed/29404858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-017-0223-7
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