Bayesian estimation of cyclosporin exposure for routine therapeutic drug monitoring in kidney transplant patients

AIMS: AUC-based monitoring of cyclosporin A (CsA) is useful to optimize dose adaptation in difficult cases. We developed a population pharmacokinetic model to describe dose-exposure relationships for CsA in renal transplant patients and applied it to the Bayesian estimation of AUCs using three blood...

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Bibliografske podrobnosti
Main Authors: Bourgoin, Hélène, Paintaud, Gilles, Büchler, Matthias, Lebranchu, Yvon, Autret-Leca, Elisabeth, Mentré, France, Guellec, Chantal Le
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2005
Teme:
Pharmacokinetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884958/
https://ncbi.nlm.nih.gov/pubmed/15606436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02200.x
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