TRAF6 regulates EGF-induced cell transformation and cSCC malignant phenotype through CD147/EGFR

TRAF6, a well-known adapter molecule, plays pivotal role in TLR/IL-1R associated signaling pathway. Although TRAF6 has been shown to have oncogenic activity in various malignant tumors, the details remain unclear. In this study, we demonstrated that TRAF6 facilitates Ras (G12V) and EGF-induced cellu...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Zhang, Xu, Wu, Lisha, Xiao, Ta, Tang, Ling, Jia, Xuekun, Guo, Yeye, Zhang, JiangLin, Li, Jie, He, Yijing, Su, Juan, Zhao, Shuang, Tao, Juan, Zhou, Jianda, Chen, Xiang, Peng, Cong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833715/
https://ncbi.nlm.nih.gov/pubmed/29463844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0030-1
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