TRAF6 regulates EGF-induced cell transformation and cSCC malignant phenotype through CD147/EGFR

TRAF6, a well-known adapter molecule, plays pivotal role in TLR/IL-1R associated signaling pathway. Although TRAF6 has been shown to have oncogenic activity in various malignant tumors, the details remain unclear. In this study, we demonstrated that TRAF6 facilitates Ras (G12V) and EGF-induced cellu...

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Pubblicato in:Oncogenesis
Autori principali: Zhang, Xu, Wu, Lisha, Xiao, Ta, Tang, Ling, Jia, Xuekun, Guo, Yeye, Zhang, JiangLin, Li, Jie, He, Yijing, Su, Juan, Zhao, Shuang, Tao, Juan, Zhou, Jianda, Chen, Xiang, Peng, Cong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833715/
https://ncbi.nlm.nih.gov/pubmed/29463844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0030-1
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