TRAF6 regulates EGF-induced cell transformation and cSCC malignant phenotype through CD147/EGFR

TRAF6, a well-known adapter molecule, plays pivotal role in TLR/IL-1R associated signaling pathway. Although TRAF6 has been shown to have oncogenic activity in various malignant tumors, the details remain unclear. In this study, we demonstrated that TRAF6 facilitates Ras (G12V) and EGF-induced cellu...

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Bibliografiske detaljer
Udgivet i:	Oncogenesis
Main Authors:	Zhang, Xu, Wu, Lisha, Xiao, Ta, Tang, Ling, Jia, Xuekun, Guo, Yeye, Zhang, JiangLin, Li, Jie, He, Yijing, Su, Juan, Zhao, Shuang, Tao, Juan, Zhou, Jianda, Chen, Xiang, Peng, Cong
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group UK 2018
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5833715/ https://ncbi.nlm.nih.gov/pubmed/29463844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0030-1
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TRAF6 regulates EGF-induced cell transformation and cSCC malignant phenotype through CD147/EGFR

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