A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3

Increasing evidences reveal that autophagy inhibitor could enhance the effect of chemotherapy to cancer. However, few autophagy inhibitors are currently approved for clinical application in humans. Berbamine (BBM) is a natural compound extracted from traditional Chinese medicine that is widely used...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Death Dis
Main Authors: Fu, Ruoqiu, Deng, Qin, Zhang, Hongwei, Hu, Xiaoye, Li, Yunong, Liu, Yanxia, Hu, Jinjiao, Luo, Qingsong, Zhang, Yanhao, Jiang, Xiuxing, Li, Lirong, Yang, Chong, Gao, Ning
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2018
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833711/
https://ncbi.nlm.nih.gov/pubmed/29445175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0276-8
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