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Downregulation of MYO1C mediated by cepharanthine inhibits autophagosome-lysosome fusion through blockade of the F-actin network
Abstract Background MYO1C, an actin-based motor protein, is involved in the late stages of autophagosome maturation and fusion with the lysosome. The molecular mechanism by which MYO1C regulates autophagosome-lysosome fusion remains largely unclear. Methods Western blotting was used to determine the...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2019-11-01
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| Seria: | Journal of Experimental & Clinical Cancer Research |
| Hasła przedmiotowe: | |
| Dostęp online: | http://link.springer.com/article/10.1186/s13046-019-1449-8 |
| Etykiety: |
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