A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3

Increasing evidences reveal that autophagy inhibitor could enhance the effect of chemotherapy to cancer. However, few autophagy inhibitors are currently approved for clinical application in humans. Berbamine (BBM) is a natural compound extracted from traditional Chinese medicine that is widely used...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Fu, Ruoqiu, Deng, Qin, Zhang, Hongwei, Hu, Xiaoye, Li, Yunong, Liu, Yanxia, Hu, Jinjiao, Luo, Qingsong, Zhang, Yanhao, Jiang, Xiuxing, Li, Lirong, Yang, Chong, Gao, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833711/
https://ncbi.nlm.nih.gov/pubmed/29445175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0276-8
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