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Nicotine associated breast cancer in smokers is mediated through high level of EZH2 expression which can be reversed by methyltransferase inhibitor DZNepA

Recent studies show substantial growth-promoting properties of nicotine (NIC) in cancer, which is a combined outcome of genetic and epigenetic alterations. However, the role of epigenetic modifiers in response to NIC in breast cancer is less studied. In the present study, for the first time we have...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Kumari, Kanchan, Das, Biswajit, Adhya, Amit, Chaudhary, Sanjib, Senapati, Shantibhusan, Mishra, Sandip K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833686/
https://ncbi.nlm.nih.gov/pubmed/29396474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0224-z
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