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Nicotine associated breast cancer in smokers is mediated through high level of EZH2 expression which can be reversed by methyltransferase inhibitor DZNepA

Recent studies show substantial growth-promoting properties of nicotine (NIC) in cancer, which is a combined outcome of genetic and epigenetic alterations. However, the role of epigenetic modifiers in response to NIC in breast cancer is less studied. In the present study, for the first time we have...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Kumari, Kanchan, Das, Biswajit, Adhya, Amit, Chaudhary, Sanjib, Senapati, Shantibhusan, Mishra, Sandip K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833686/
https://ncbi.nlm.nih.gov/pubmed/29396474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0224-z
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