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Glycogen synthase kinase-3β inhibition promotes lysosome-dependent degradation of c-FLIP(L) in hepatocellular carcinoma
Glycogen synthase kinase-3β (GSK-3β) is a ubiquitously expressed serine/threonine kinase involved in a variety of functions ranging from the control of glycogen metabolism to transcriptional regulation. We recently demonstrated that GSK-3β inhibition triggered ASK1-JNK-dependent apoptosis in human h...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833564/ https://ncbi.nlm.nih.gov/pubmed/29445085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0309-3 |
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