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Resibufogenin suppresses transforming growth factor‐β‐activated kinase 1‐mediated nuclear factor‐κB activity through protein kinase C‐dependent inhibition of glycogen synthase kinase 3

Resibufogenin (RB), one of the major active compounds of the traditional Chinese medicine Chansu, has received considerable attention for its potency in cancer therapy. However, the anticancer effects and the underlying mechanisms of RB on pancreatic cancer remain elusive. Here, we found that RB inh...

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Publicado en:Cancer Sci
Autores principales: Liu, Lu, Liu, Yang, Liu, Xiaojia, Zhang, Na, Mao, Genxiang, Zeng, Qingxuan, Yin, Mingxiao, Song, Danqing, Deng, Hongbin
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215888/
https://ncbi.nlm.nih.gov/pubmed/30168902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13788
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